More information: James Attwater et al, Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme, Nature Chemistry (2025).

A research team used complete, telomere-to-telomere genome assemblies to predict the location of these structures. This data allows the study of previously unexplored areas due to their repetitive ...

The research, published today as a Reviewed Preprint in eLife, is described by the editors as a landmark study with compelling evidence on how an important player in DNA repair—the RAD51 ...

New research predicts the location of DNA sequences that can form structures besides the canonical double helix — non-B DNA — in the recently released telomere-to-telomere genomes of the great apes, ...

Liu: It's a really complicated topic. In really broad terms, replication stress is when the process of DNA replication — by which DNA is duplicated during the cell cycle — is slowed down or ...

A new technique could use a person’s DNA to reconstruct a 3D model of their face. Researchers have devised a computational tool, called Difface, that uses the differences between single letters of the ...

Reconstructing a face from DNA — even without a name — could undermine de-identification. This the core promise of most DNA testing companies that state your genetic data stays anonymous.

2. Pecorino LT, Verhaak RGW, Henssen A, Mischel PS. Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance. Biochem Soc Trans 2022;50:1911-1920.

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

This technique, called volumetric DNA microscopy, creates a 3D image of an entire organism from the inside out, giving scientists an unprecedented view of genetic sequences and where they are ...

The company recommends updating to Backup & Replication version 12.3.1 (build 12.3.1.1139), which includes patches for the flaw. According to cybersecurity firm watchTowr, which was credited for ...

When not undergoing replication, DNA molecules float freely within the cytoplasm of a cell. This makes them available to the accessory molecules that organize and repair DNA.