The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...
The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...
Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...
In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...
Papers presented at a conference held on Aug. 6-11, 1989 in East Glacier Park, Montana. https://siris-libraries.si.edu/ipac20/ipac.jsp?&profile=liball&source ...
A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making ...
This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression. As the center of protein synthesis, ribosomes influence liver regeneration, ...
Scientists at St. Jude Children’s Research Hospital report that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study “mRNA ...
Trypanosome is a single-celled parasite that takes an extensive human and economic toll due to its involvement in causing sleeping sickness in humans and a similar disease in cattle. The parasite, ...
Lariocidin hits drug-resistant bacteria where others fail — by hijacking the ribosome at a new site, bypassing defences, and opening the door to a new generation of antibiotics. Lariocidin, a ...
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