Internal ribosome entry sites (IRESs) are highly structured RNA elements that permit the recruitment of ribosomes for translation initiation independent of the conventional 5′-cap mechanism. Viruses ...

Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A molecular framework of how ...

Northwestern Engineering synthetic biologists have expanded the capabilities of engineered ribosomes as a vehicle to synthesize novel biopolymers, setting the stage for developing new medications and ...

Fears about the COVID-19 vaccine's side effects have left some folks hesitant to join the immunization party, inadvertently affecting broader disease prevention. A recent study in Nature unveils a ...

A research team from the Engelhardt Institute of Molecular Biology in Russia have shown that Nsp1 – a non-structured protein present in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...