This study addresses an important question in liver biology: how zonal hepatocytes balance survival and proliferation following injury; using spatial transcriptomics, mechanistic perturbations, and ...

Abstract: Single-cell RNA sequencing (scRNA-seq) provides a high throughput, quantitative and unbiased framework for scientists in many research fields to identify and characterize cell types within ...

Alternative splicing exhibits lineage-specific variability, with mammals and birds reaching the highest levels despite conserved intron-rich architectures, while unicellular eukaryotes and prokaryotes ...

Under the terms of the deal, Gilead will put down $120 million in an upfront payment and will promise up to $1.52 billion in ...

Explore the impact of lysosomal lipid recycling in a rare multi-organ disorder linked to the SPNS1 gene mutations.

Scientists armed bacteria with cancer-killing viruses that infiltrate tumors, evade immunity, and attack from within.

Researchers create an artificial genetic system mimicking reverse translation, converting music into DNA to explore ...

Stroke risk evolves across the lifespan, with distinct sex-specific differences that remain underappreciated in both research ...

UD researchers study how protein coatings influence nanoparticles' ability to avoid immune clearance and reach their ...

A new collaborative study from the Wyss Institute leveraged a “breathing” human lung alveolus chip model of influenza A ...

Organoids are three-dimensional, self-organizing structures derived from stem cells that faithfully mimic the complexity of ...

Greater than 90% depletion of B cells within 12 hours of a single dose of AAN-14xMultiple redosing of AAN-14x at desired intervals with no evidence of hepatic or other toxicityRemarkable tumor ...