He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...

As the nation mourns the victims of the devastating Air India crash in Ahmedabad, science is quietly stepping in to offer solace to grieving families.

We show that inhibition of replication by DarT is reversible and accompanied by extensive ADP-ribosylation at the origin of replication (OriC). In addition, we observe ADP-ribosylation across the ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

Scientists see the first steps of DNA unwinding Scientists report the most detailed account yet of the very first steps in DNA replication, an event that all life uses to grow and reproduce Peer ...

The genetic information on organisms is stored in the cell nucleus in the form of higher-ordered DNA structures. Here, we use DNA framework nanostructures (DFNs) to simulate the compaction and ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

Today, researchers are making steps toward a full understanding of the molecular checks and balances that have evolved in order to ensure that each origin initiates DNA copying once and only once ...

Yap interacts with Rif1, a major DNA replication timing factor, and functions as a brake to control the DNA replication program in Xenopus early embryos and post-embryonic stem cells.

Three meteorites contain the molecular building blocks of DNA and its cousin RNA, scientists recently discovered. A subset of these building blocks had been detected in meteorites before, but the ...

Group of Cell Cycle Control, Program of Immunology and Tumor Biology, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil DNA replication must be precisely controlled in order to ...