This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

Chalcone synthase (CHS) is pivotal for the biosynthesis of flavonoid antimicrobial phytoalexins and anthocyanin pigments in plants. It produces chalcone by condensing one p-coumaroyl- and three ...

国家前瞻性布局的重大科技基础设施——“多模态跨尺度生物医学成像设施”的建成启用，标志着我国在生物医学成像领域拥有了覆盖纳米至米级分辨率、毫秒至数年时间尺度的强大综合观测能力，为生命科学研究开辟了前所未有的可能性（点此复习）。为推动成像能力与RNA前沿研究的深度交叉融合，国家自然科学基金委员会于2024年召 ...

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...

Solomon’s seal plants have long been used in traditional medicine, but identifying species can be difficult. New research mapped the complete genetic code of Polygonatum sinopubescens, revealing its ...

This study presents a large, systematically curated catalog of non-canonical open reading frames (ncORFs) in human and mouse by reanalyzing nearly 400 Ribo-seq datasets using a standardized pipeline; ...