Heart failure is a pressing worldwide public-health problem with millions of patients having worsening heart failure. Despite all the available therapies, the condition carries a very poor prognosis.

Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell imaging ...

Coffee contains caffeine and other bioactive compounds, including antioxidants like chlorogenic acids plus cafestol, kahweol, and trigonelline, though amounts vary per cup. Caffeine blocks adenosine, ...