Objective Daptomycin, a cyclic lipopeptide that exhibits rapid, concentration-dependent bactericidal activity in vitro against a broad spectrum of Gram-positive pathogens, has now, since 2003, been ...

Statistical heterogeneity will be estimated with the I 2 statistic. Risk of small study effects will be assessed using funnel plots and Egger test. Studies will be analysed for time-varying and ...

It’s not advisable to create a multi-stepped patient funnel, looking at total population and prevalence through to target population, then number diagnosed, biomarker tested treated, etc.

Dosing a statin (rosuvastatin) every other day (EOD) may provide significant lipoprotein changes while avoiding common adverse effects in this statin-intolerant population. Objective: To determine ...