Transfer RNA (tRNA) is a small nucleic acid (typically 76 nucleotides) that forms binary complexes with proteins, such as aminoacyl tRNA synthetases (RS) and Trbp111. The latter is a widely ...

Results of a multinational genetic study suggest that defects in transfer RNA (tRNA) processing may be responsible for many cases of the neurodegenerative disease pontocerebellar hypoplasia (PCH).

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

UMD researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) Transfer RNA (tRNA) molecules are responsible for delivering ...

A distinction is made between different types of RNA with different functions. For example, tRNA (transfer RNA) is an adapter molecule that deciphers the genetic code on mRNA (messenger RNA ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...