Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Transfer RNA (tRNA) is a small nucleic acid (typically 76 nucleotides) that forms binary complexes with proteins, such as aminoacyl tRNA synthetases (RS) and Trbp111. The latter is a widely ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) Transfer RNA (tRNA) molecules are responsible for delivering ...

UMD researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.

It is analogous to Southern blotting, which is used to analyze DNA. This protocol describes the transfer of RNA from agarose gels to nylon membranes and the fixation of the RNA to the membrane 1,2,3.

A distinction is made between different types of RNA with different functions. For example, tRNA (transfer RNA) is an adapter molecule that deciphers the genetic code on mRNA (messenger RNA ...