Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U ...

The authors provided convincing data for a key role of Msi2 in lung adenocarcinoma tumor progression and growth. Multiple evidences using Msi2 knock-out genetic mouse model and shRNA knock-down in ...

To enhance exploration on tumor stem-like cells (TSCs) without altering their cellular biological characteristics, researchers advocate for application of single-cell-derived tumor-spheres (STSs).

Together with the company’s vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry’s ...

Subsequently, the primary AT2 cells were isolated for in vitro analyses, which included organoid and tumor sphere formation assays to assess self-renewal and transformation capacities.

Illumina also reported that the in vitro diagnostic version of its assay—known as TruSight Oncology Comprehensive—has begun shipping to U.S. clinical customers. The pan-cancer tissue profiling ...

Researchers have developed an antibody that prevents the activation of the Dickkopf 1-Cytoskeleton-associated protein 4 (DKK1-CKAP4) pathway, which is important for tumor growth in several cancers ...

This work is published in Nature in the paper, “ Gut microbiota carcinogen metabolism causes distal tissue tumours. ” Researchers have previously shown that if mice are exposed to N-butyl-N ...

(d) Colony formation assay showed impaired colony formation ability in C666-1 cells after SOX2 knock-down by siRNA treatment (n = 3; student’s t-test). (e) Representative pictures and growth curve of ...

Interestingly, the formation of tumors in mice receiving transplants from cultures from which EPHA2 had been removed was vastly suppressed. Taken together, these results point to the importance of ...

"Tackling the hurdle of tumor formation in stem cell therapies." ScienceDaily. ScienceDaily, 31 May 2024. <www.sciencedaily.com / releases / 2024 / 05 / 240531122415.htm>.

Background: The detection of minimal residual disease (MRD) through circulating tumor DNA (ctDNA) analysis provides an advanced molecular method for early identification of surgical patients at high ...