A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

In a first-of-its-kind project, researchers are tapping into the power of citizen science to collect DNA samples from hundreds of lakes worldwide. Not only will the resulting cache of ...

The discovery of the twisting switch resolves a long-standing question about how the DNA repair protein RNF168, which has a tendency to cause uncontrolled signaling, is switched off.

Light bulb moment for understanding DNA repair switches. ScienceDaily. Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 04 / 250414124702.htm. University of Birmingham.

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Moreover, understanding these methylation patterns offers insight into why individuals may exhibit varied levels of inflammation and disease risk. "There are gaps in diversity in epigenome-wide ...