MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

a converging fork will complete replication. However, if a single fork stops within the rDNA or telomere, it will result in a region of DNA that cannot be replicated. Therefore, the rDNA ...

The role of chromatin structures during transcription via enhancer-promoter interactions is well established. Less understood is how nuclear architecture influences the plethora of chromatin ...

Univ Brest, Ifremer, Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Plouzané, France In my opinion, these discoveries challenge the “classical” models of DNA replication. Archaea are not ...

Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...