Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation.

All life on Earth is unified by its use of a shared set of component chemical compounds and reactions, providing a detailed model for universal biochemistry. However, this notion of universality is ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...

When two defective gene variants combine, normal protein function can sometimes be restored.

Researchers identified AlCas12a, a compact, versatile enzyme that improves CRISPR gene editing and enables faster molecular ...

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function. These ...