In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...
Optimizing dsRNA Removal in IVT mRNA: Strategies for Enhanced Translation and Reduced Immunogenicity
Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications. Even ...
The 2023 Nobel Prize in physiology or medicine will go to Katalin Karikó and Drew Weissman for their discovery that modifying mRNA — a form of genetic material your body uses to produce proteins — ...
More than a century ago, the anatomist Santiago Ramón y Cajal unveiled his incredibly detailed drawings of neurons. From these, he posited that neurons were the main building blocks of the brain and ...
RNA-4359 has advanced into the Phase 2 portion of the ongoing Phase 1/2 trial CAMBRIDGE, MA / ACCESS Newswire / October 12, ...
Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.
Researchers from the Broad Institute and Massachusetts Institute of Technology (MIT) have engineered multi-tailed mRNAs that boost mRNA activity levels in cells by as much as 20x and last 2-3 times ...
André O. Hudson receives funding from the National Institutes of Health. We asked André O. Hudson, a biochemist and microbiologist at the Rochester Institute of Technology, to explain how basic ...
An ongoing concern for scientists is that there will be across-the-board funding cuts. This is already happening in mRNA research, where reductions affected coronavirus-related projects. During the ...
In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...
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