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tRNA 与 rRNA 的翻译 “基础设施” 修饰 tRNA 的反密码子环与可变环区域的假尿苷化(如 tRNA Lys 的 Ψ34 位点)可增强其与 mRNA 密码子的配对稳定性,减少翻译错误率。 核糖体 RNA(rRNA)的假尿苷化(如人类 28S rRNA 的 Ψ4484 位点)则通过重塑核糖体大亚基的构象,调控肽基转移酶中心的催化效率,进而 ...
Science:揭示特定trna通过招募CCR4-NOT复合物促进mrna衰减机制. 这项研究表明,trna 还能发挥额外的功能,即不仅能解码 mrna 和传递氨基酸,还能在翻译 ...
通过整合核糖体 rna(rrna)、转运 rna(trna)和信使 rna(mrna)的 Ψ 化学计量学数据,以及 mrna 丰度和多聚核糖体分析数据,研究人员揭示了通过 Ψ 修饰对翻译效率的多层调控机制。rrna 假尿苷化能够在全局层面控制翻译过程,尽管不同 rrna Ψ 位点的影响存在差异。
Please use one of the following formats to cite this article in your essay, paper or report: APA. Cheriyedath, Susha. (2023, April 07). Types of RNA: mRNA, rRNA and tRNA.
Ribosomal RNA (rRNA) is a type of non-coding RNA that is a crucial component of ribosomes, the cellular machinery responsible for protein synthesis.Non-coding RNA refers to RNA molecules that are not ...
Transfer RNA (tRNA) links the mRNA sequence with its corresponding amino acid, ensuring that proteins are stitched together correctly as instructed by DNA. Ribonucleic acid ...
Alltrna Inc. has presented new preclinical data on the company’s first transfer RNA (tRNA) development candidate, AP-003. Alltrna Inc. has presented new preclinical data on the company’s first ...
The first patients have been dosed in a phase 3 trial of an mRNA-based seasonal influenza vaccine developed by Pfizer and BioNTech, which may offer quicker production and greater efficacy than ...
Drugs based on mRNA have taken off since the development of mRNA-based COVID-19 vaccines. Jake Becraft, PhD, CEO and co-founder of Strand Therapeutics, spoke on a panel about DNA supply at ...
"Ethris and Thermo Fisher partner on mRNA solutions" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand.. The information on this site has been included in ...
A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at the University of Pittsburgh School ...
A new type of mRNA vaccine is more adaptable to mutating viruses like SARS-CoV-2 and the bird flu, according to research from the University of Pittsburgh.
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