RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which ... ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures ...

To determine the mechanism underlying the flow of genetic information, it is important to understand the relationship between a tRNA and its binding enzyme, a member of the aminoacyl-tRNA synthetase ...

Apart from these studies on regulatory RNAs, recent genome-wide research also reveals the general role of mRNA structure in a variety of post-transcriptional regulations such as RNA maturation, RNA ...

Gene products are often proteins, however non-protein coding genes can encode functional RNA, including ribosomal RNA (rRNA), transfer RNA (tRNA ... of cytoplasmic mRNA decay and comment on ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

1958年，弗朗西斯・克里克提出了中心法则，提出遗传信息从 DNA 转录为 RNA，再经翻译指导蛋白质合成，随后蛋白质参与生命活动这一流程，看似一气呵成，实则存在问题。 若仔细观察，便会发觉此流程不够简洁，RNA 的存在略显累赘。毕竟，越简单的系统往往越高效、越易实现，繁琐的系统则耗能多且不易形成。 从结构看，RNA 与 DNA ...

After hours: January 31 at 7:59:52 p.m. EST ...