RNA 2'-氧-甲基化广泛分布在rRNA和m RNA上, 具有重要的功能, 由于检测方法的局限, 其研究仍具有挑战。为深入理解该领域, 本文全面综述了RNA2'-氧-甲基化的分布、检测方法、功能以及疾病中的作用和治疗潜力。导 ...

To achieve these goals, it is crucial to understand the role of eIF5B in translational regulation. This review recapitulates eIF5B’s regulatory roles in the translation initiation of viral mRNA as ...

Codon optimization takes into account factors such as codon usage bias, tRNA abundance, GC content, and RNA secondary structure. By carefully selecting codon combinations, researchers can improve ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking w.

The global fight against cancer is at a pivotal moment. A breakthrough in Russia promises to redefine cancer treatment, with the country announcing its first mRNA cancer vaccine. This revolutionary ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

Department of Chemistry, University of California, Berkeley, California 94720, United States Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, United ...

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

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