Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

Using MapID-tRNA-seq, the researchers were able to map both tRNA modifications and expressions, discovering that some modification profiles from cell to cell largely remain unchanged.

The natural and overlapping history of tRNA and rRNA reveals that: (1) the tRNA cloverleaf structure unfolded prior to the appearance of a fully functional ribosomal core, (2) the primordial role of ...