The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

Background When children and young people (CYP) report their own suspected adverse drug reactions (ADRs), different patterns of drugs and symptoms are noted. A new guide to reporting suspected ADRs ...

Introduction Children are at higher risk of medication errors due to the complexity of drug prescribing and administration in this patient group. Intravenous (IV) paracetamol overdose differs from ...

Objectives To provide up-to-date information on the use of long-term ventilation (LTV) in the UK paediatric population and to compare the results with data collected 10 and 20 years previously. Design ...

Many additives, some of which have no nutritional value, can be legally used in processed foods. They intensify colour, thicken, increase shelf life and enhance flavour. Regulatory authorities issue ...

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

For anyone, undergoing surgery is stressful. For children on the autism spectrum, it can be even more traumatic. Sensory differences are present in the majority of children on the autism spectrum,1 ...

Oral health is part of general health and well-being and contributes to the development of a healthy child. The most common oral disease affecting young children is dental caries (figure 1), which is ...

Objective A recent review reported that the WHO 2006 growth standards reflect a smaller head circumference at 24 months than seen in 18 countries. Whether this happens in early infancy and to what ...

Objectives Historically diagnoses of Trisomy 13 (T13) and Trisomy 18 (T18) have been associated with a very poor prognosis. Median survival of full T18 is 14days, T13 is 10days and 3-month survival is ...

Conclusion Our findings support the AAP’s recommendation to avoid obtaining a UC in female infants aged 22–90 days with a negative urinalysis. Blood tests demonstrated low performance in predicting a ...