Alcohol-based hand sanitisers, if ingested, can have toxic effects and may even be lethal. Preventable deaths from ingesting hand sanitisers have been identified. This article describes two Prevent ...

BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and ...

Introduction: High-quality randomised controlled trials (RCTs) provide the most reliable evidence on the comparative efficacy of new medicines. However, non-randomised studies (NRS) are increasingly ...

Evidence-based medicine and coroners’ concerns Evidence-based medicine incorporates clinical expertise, patient values and the best external evidence. 8 Although systematic reviews and randomised ...

Journal clubs, typically involving a group of health professionals or trainees who discuss recent study findings, have long ...

The effects of statins in the elderly are better informed by absolute effects and the number needed to evaluate the benefit to harm balance. Such an approach enables patients to make more informative ...

Introduction The burden of death due to firearms is an ongoing public health problem in the USA. US men had a 21% life expectancy loss due to firearms compared with men from other countries. 1 In 2016 ...

Data extraction is the process of a systematic review that occurs between identifying eligible studies and analysing the data, whether it can be a qualitative synthesis or a quantitative synthesis ...

Introduction High rates of long COVID or post-acute sequelae of COVID-19 (PASC) continue to be reported in academic journals and subsequently filtered to the public. For instance, the Centers for ...

Objective To assess the methodological and reporting quality of systematic reviews that comprise the American Psychiatric Association (APA) Practice Guideline for the Treatment of Patients with ...

External validity is a construct that attempts to answer the question of whether we can use the results of a study in patients other than those enrolled in the study. External validity consists of two ...

Clinical practice guideline (CPG) panels are expected to abide by standards that ensure their processes are multidisciplinary, systematic and unbiased.1 Unfortunately, many CPGs fail to satisfy these ...