CK, creatine kinase; DAT, direct antiglobulin test; EMA, antiendomysial antibody; LDH, lactate dehydrogenase.; TSH, thyroid stimulating hormone; tTG, tissue ...

Determining severity of illness and undertaking an adequate risk assessment is a fundamental part of acute paediatric practice. This review highlights physiology, communication, heuristics and ...

Design : Randomised controlled trial. Allocation : Randomisation was done by university staff. Allocation was concealed using sealed envelopes that were sequentially numbered. Blinding : All patients, ...

Commentary This study from the Childhood Absence Epilepsy Study Group in the USA is the first blinded trial comparing the three most commonly used antiepileptic drugs (AEDs) in Childhood Absence ...

There are no outcomes-based commissioning structures in child health. This needs to change. Preschool wheeze is a very common condition. Many families present at emergency departments with their ...

Epilepsy is the most common significant long-term neurological condition of childhood. The prevalence in children in the UK is approximately 4 per 1000 children. It affects 1 in 220 children and young ...

Introduction Down’s syndrome (DS) occurs in 1 in every 1000 live births 1 and is the most frequent chromosomal abnormality seen in liveborn infants. It is caused by having an extra full or partial ...

Renal ultrasound is one of the most frequently requested imaging studies in children. Indications include urinary tract infection (UTI), renal dysfunction and to exclude structural abnormalities—for ...

Array-comparative genomic hybridisation (array-CGH) is a relatively new test that permits close scrutiny of chromosomal structure to detect genomic microdeletions and microduplications that are ...

Table 6 Clinical signs and symptoms typical of upper airway obstruction at different anatomical levels ...

Infection Sepsis creates an increased metabolic demand. The infant may be unable to meet the increased oxygen requirements of the tissues leading to peripheral vasoconstriction and cyanosis. In ...

The National Institute for Health and Clinical Excellence neonatal jaundice guidelines recommend checking the bilirubin level in all infants with visible jaundice. The gold standard for this ...