Background Bronchoscopic limitations in reaching peripheral pulmonary lesions (PPLs) can compromise biopsy sensitivity, ...

1 Division of Paediatric Respirology and Department of Physiotherapy, Cystic Fibrosis Clinic, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada 2 Division ...

1 Department of Palliative Medicine, Royal Marsden and Royal Brompton NHS Foundation Trusts, London, UK 2 Department of Palliative Care, Policy and Rehabilitation, King's College London, Cicely ...

Background Previous studies have shown that the incidence of idiopathic pulmonary fibrosis (IPF) is rising in the UK and USA. Death registrations and primary care data were used to determine the ...

1 King's College London, Department of Asthma, Allergy and Respiratory Science, London, UK 2 King's College Hospital, Department of Respiratory Medicine, London, UK 3 National Heart and Lung Institute ...

Background: Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) ...

12 Department of Respiratory Medicine, Odense University & University of Southern Denmark, Denmark/University of Manchester, Academic Health Science Centre, Manchester, UK 13 Department of Respiratory ...

Background: Bronchiolitis obliterans (BO) is an uncommon and severe form of chronic obstructive lung disease in children that results from an insult to the lower respiratory tract. Methods: A ...

Background Despite vaccination, influenza infection is still a major health burden, especially in people aged >65 years, immunocompromised or with respiratory disease. Current intramuscular influenza ...

The past 5 years have seen an explosion of interest in the use of artificial intelligence (AI) and machine learning techniques in medicine. This has been driven by the development of deep neural ...

The COVID-19 pandemic has led to an unprecedented surge in hospitalised patients with viral pneumonia. The most severely affected patients are older men, individuals of black and Asian minority ...

Introduction Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are ...