Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK Correspondence to: Dr C S Garrard, Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK; chris.garrard{at}clinical-medicine ...

Background Non-invasive ventilation (NIV) is an effective form of treatment in patients with obesity hypoventilation syndrome (OHS) who have concomitant severe obstructive sleep apnoea (OSA). However, ...

Background Despite exacerbations of chronic obstructive pulmonary disease (COPD) being both common and often fatal, accurate prognostication of patients hospitalised with an exacerbation is difficult.

Objective Little is known about how lower respiratory tract infections (LRTIs) before chronic obstructive pulmonary disease (COPD) are associated with future exacerbations and mortality. We ...

Background CFTR modulators have transformed cystic fibrosis (CF) treatment, but individual responses vary even among patients with identical CFTR genotypes. This underscores the need for predictive ...

Background The use of 3D imaging with navigation bronchoscopy has increased with the introduction of mobile cone-beam CT (mCBCT). Shape-sensing robotic-assisted bronchoscopy (ssRAB) integrated with ...

1 School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK 2 Directorate of Medicine, Norfolk and Norwich University Hospital, Norwich, Norfolk, UK ...

Hypothesis The risk of Venous Thromboembolism (VTE) including Pulmonary Embolism (PE) increases proportionately with the level of d-dimers. Introduction The risk of PE/VTE is low when the values of ...

Objective Vaping may increase the cytotoxic effects of e-cigarette liquid (ECL). We compared the effect of unvaped ECL to e-cigarette vapour condensate (ECVC) on alveolar macrophage (AM) function.

Department of Child Health, Queen’s University of Belfast, Clinical Institute, Belfast, UK All children experience head colds and many consult their doctor because of associated coughing.1 Cough with ...

Background Previous studies have shown that the incidence of idiopathic pulmonary fibrosis (IPF) is rising in the UK and USA. Death registrations and primary care data were used to determine the ...

1 Interstitial Lung Disease Program and Autoimmune Lung Center, National Jewish Health, Denver, Colorado, USA 2 Division of Psychosocial Medicine, National Jewish Health, Denver, Colorado, USA 3 ...