Department of Cardiology, Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Cardiovascular disease (CVD) is the predominant cause of death globally, accounting for ≈30% of deaths each year. 1 The prevalence of CVD among adults (aged ≥20 years) in the United States was 48.6% ...

Acute fulminant myocarditis (AFM) is characterized by sudden, severe cardiac inflammation causing hemodynamic instability or arrhythmia. 1 Currently, no approved medical therapy exists for AFM. Janus ...

A comprehensive literature search was conducted from July 2023 to April 2024. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants were identified ...

Pulmonary hypertension (PH) is now defined as mean pulmonary artery pressure >20 mm Hg according to the updated clinical classification from the 6th World Symposium of Pulmonary Hypertension (WSPH) ...

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...

BACKGROUND: Circular RNAs (circRNAs) have been gradually revealed to regulate the progression of heart disease in depth, showing their clinical significance. However, a mass of cardiac circRNAs still ...

Time-of-day significantly influences the severity and incidence of stroke. Evidence has emerged not only for circadian governance over stroke risk factors, but also for important determinants of ...

BACKGROUND: T cells are central to the immune responses contributing to hypertension. LGMN (legumain) is highly expressed in T cells; however, its role in the pathogenesis of hypertension remains ...