TDP-43 Conference Marks Concerted Effort to Finally Snag Biomarkers. Add To My AlzForum; 30 Jun 2025. Steps Forward: Immunoassays for cryptic HDGFL2 flag TDP-43 proteinopathy in diverse disorders.

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

Species: Mouse Genes: MAPT Mutations: MAPT P301L Modification: MAPT: Transgenic Disease Relevance: Alzheimer's Disease, Frontotemporal Dementia Strain Name: Thy1-hTau.P301L Genetic Background: FVB/N ...

Ivonne Suridjan Roche; Posted: 06 Oct 2021 This publication references Aβ 42/40 prototype assays currently in feasibility testing as potential blood-based biomarkers for AD within Roche Diagnostics; ...

Li-Huei Tsai, Massachusetts Institute of Technology, Boston, and colleagues some years ago turned light and sound into a therapy.They called it GENUS, short for gamma entrainment using sensory stimuli ...

David Holtzman Washington University; Posted: 27 Jul 2018 The new data clearly showed that the anti-Aβ antibody BAN2401 was able to significantly remove amyloid from brain, as quantified by ...

04 May 2023. Score another one for amyloid immunotherapy. The anti-pyroglutamated amyloid antibody donanemab has posted positive top-line results in the Phase 3 Trailblazer-Alz2 study, according to an ...

20 Jan 2022. After months of uncertainty, the hammer fell for Biogen: In a draft decision released January 11, the Centers for Medicare and Medicaid Services proposed to cover the anti-amyloid ...

This database is a repository of normal genetic variability, designed to be a tool for researchers who study neurodegenerative disease. It contains whole-exome sequencing results from nearly 500 ...

28 Sep 2022. Eisai and Biogen yesterday announced positive topline results from the Phase 3 Clarity trial of their anti-amyloid antibody lecanemab.The drug slowed decline on the primary endpoint, ...

17 Aug 2018. After years of fits and starts, anti-amyloid immunotherapies are finally hitting their target effectively. At least four drugs have now demonstrated the ability to clear plaques from the ...

25 Jan 2024. Not so long ago, a blood test for Alzheimer’s disease seemed a pipe dream. Now, after years of study, the field is awash with sensitive assays that signal the proteopathic culprits Aβ and ...