These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Remnants of transposable elements (TEs) are widely expressed throughout mammalian embryo development. Originally infesting our genomes as selfish elements and acting as a source of genome instability, ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Collecting duct carcinoma (CDC) remains a lethal and aggressive form of kidney cancer with no effective treatment, primarily because of our limited understanding of its underlying molecular ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

Ago2 differentially regulates oncogenic and tumor-suppressive miRNAs in cancer cells. This discrepancy suggests a secondary event regulating Ago2/miRNA action in a context-dependent manner. We show ...

imageimageThe systemic control of tissue fibrosis by metabolic organs remains poorly understood. This study identifies procollagen C-endopeptidase enhancer-1 (PCPE-1) as an adipokine released from ...

imageimageHypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor hypoxia promotes immune evasion by autophagy-mediated downregulation ...

imageimageThe long-non-coding RNA aal1 (ageing-associated lncRNA) promotes the longevity of non-dividing cells likely by attenuating their translational capacity. aal1 localizes to the cytoplasm and ...

imageimageIn 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the dinoflagellate Vulcanodinium rugosum, were found in Senegal’s fishing ...