Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024).Androgen receptor (AR) is considered ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

We demonstrate that TP53 deficiency in AML cells confers resistance to CAR T-cell therapy by inducing CAR T-cell dysfunction. We propose a model in which difficult-to-kill TP53-mutant AML cells ...

Neural stem cells (NSCs) in the mammalian brain decline rapidly with age, leading to impairment of hippocampal memory function in later life. However, the relationship between epigenetic remodeling ...

While only 1–2% of the human genome encodes proteins, the remaining repetitive, low-complexity part is poorly characterized, and was long referred to as “junk DNA” (ENCODE Project Consortium 2012; ...

The bacterial homolog DgoT (from E. coli) transports negatively charged galactonate in symport with more than one proton and, thus, differs from mammalian SLC17s in both its main substrate and ...

Macrophages not only clean the wound early for repair, but are also critically involved in all subsequent phases of proliferation and regeneration (Mirza et al, 2009; Shook et al, 2016).They ...

Arabidopsis genome encodes approximately 60 putative MAPKKKs, 10 MAPKKs, and 20 MAPKs (MAPK‐Group, 2002).MAPK cascades have been shown to regulate diverse aspects of plant biology, including plant ...