The US Environmental Protection Agency (EPA) plans to abandon landmark regulations limiting airborne mercury and greenhouse ...

The administration of US President Donald Trump has launched a full-fledged assault on science and public health;1 its “flood the zone” strategy created chaos and initially overwhelmed potential ...

Physicians treating patients with Crohn's disease face a plethora of drug choices. Yet, overall rates of clinical response seem stable over time,1 suggesting the existence of a therapeutic ceiling ...

Over the past decade, several novel immunotherapies have transformed the treatment landscape of relapsed or refractory B-cell acute lymphoblastic leukaemia. In the pivotal TOWER trial, blinatumomab—a ...

The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...

Solid organ transplantation provides life-saving and life-enhancing treatments for patients with end-stage organ failure.1,2 However, the rising global burden of non-communicable diseases (NCDs) and ...

Negotiations are ongoing in New York to agree the latest UN political declaration on non-communicable diseases (NCDs) and ...

It was by far the most difficult phone call of my life. Absolutely nothing can prepare you for telling your mother that she ...

The relationship between hormone therapy (oestrogen with or without progestogen) and breast cancer risk has been widely ...

We have witnessed weight loss of 13–15% with the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide and up to 18–23% with the dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) ...

We read with great interest the published results of the RADIOSA trial by Giulia Marvaso and colleagues.1 This well designed ...

The number of active armed conflicts globally has increased sharply in recent years, reaching levels not seen since World War ...