Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, ...
本研究针对核酸药物递送系统稳定性差、靶向性不足等挑战,创新性地利用植物病毒PVX的衣壳蛋白自组装特性,开发了可程序化装载线性mRNA和环状RNA(circRNA)的纳米递送平台。研究通过体外重组技术成功构建了尺寸可控的病毒样颗粒(VLP),并验证其可有效 ...
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, ...
This study investigates how the HIV inhibitor lenacapavir influences capsid mechanics and interactions with the nuclear pore complex. It provides important insights into how drug-induced ...
The Francis Crick Institute’s flow cytometry core has shown at ELRIG 2025 how a heterogeneous fleet of spectral, mass and ...
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