The evidence supporting the claims of the authors is solid, although the inclusion of additional data showing the mechanisms by which PLP1+ enteric glia acts on Paneth cells would have strengthened ...
Yellow color marks genes with discordant direction of change between the ileal epithelia and full-thickness ileal segments. A) Representative images of UEA-I staining of Paneth cell granules in the ...
That these three closely connected pathways—microbial signalling (NOD2), autophagy and ER stress—are all linked with IBD and affect Paneth cell function clearly suggests that bacterial handling plays ...
AMP price predictions hint at a maximum price of $0.0121 by the end of 2025 while maintaining an average price of $0.0101. In 2028, the price of AMP will range between $0.0283 and $0.0323, with an ...
Feb. 6, 2025 — A recent study investigates how polyester microdroplets, potential precursors to modern cells, could form under realistic early Earth conditions. Researchers pushed these ...
This includes antimicrobial peptides (AMP) which are produced and secreted by Paneth cells as protective agents against bacterial pathogens, as well as the dense mucus layer of mucins which is ...
Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.
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Angiogenin (ANG) is an intestine-secreted AMP with potent species-specific antimicrobial activity. ANG inhibits bacterial growth through degrading cellular RNA or disrupting cell membrane. AMPs are ...
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Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as ...