Mitochondria, the “powerhouses of the cell,” are vital cellular organelles that govern energy metabolism, maintain redox homeostasis, synthesize biomacromolecules, and initiate and transmit cell death ...

Allogeneic Stem-Cell Transplantation Using a Reduced-Intensity Conditioning Regimen Has the Capacity to Produce Durable Remissions and Long-Term Disease-Free Survival in Patients With High-Risk Acute ...

Phase III Study of Docetaxel and Cisplatin Plus Fluorouracil Compared With Cisplatin and Fluorouracil As First-Line Therapy for Advanced Gastric Cancer: A Report of the V325 Study Group In preclinical ...

Scientists at the University of Illinois at Urbana-Champaign report they have uncovered a protein that may aid efforts to fine-tune the use of immunotherapies for cancer. Their study in mice ...

Radiotherapy induces DNA damage and oxidative stress, leading to endothelial injury and blood-brain barrier disruption, which triggers neuroinflammation, microvascular dysfunction, and neuronal ...

Elimination of autoreactive developing B cells is an important mechanism to prevent autoantibody production. However, how B cell receptor (BCR) signaling triggers apoptosis of immature B cells remains ...

Ferroptosis, a distinct form of regulated cell death, is characterized by the iron-dependent accumulation of lipid peroxides, ...

AZD9291 is a novel, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), which is administered orally. It has been proven effective in non-small cell lung cancer ...

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study from ...

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, ...