Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

Hepatocellular DILI is characterized by inflammation, necrosis, and apoptosis, while cholestatic DILI involves bile plug formation and bile duct paucity. Ursodeoxycholic acid (UDCA), a widely used ...

Fat necrosis refers to dead or damaged breast tissue that often manifests as a noncancerous lump under the skin. In most cases, these lumps go away on their own and don’t return. Fat necrosis of ...

Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276000, China ...

Combining an existing small-molecule protein therapy called tumor necrosis factor related apoptosis-inducing ligand (TRAIL) with focused ultrasound (FUS) can significantly reduce tumor size and ...

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis of tumor cells but not most normal cells. Its roles in normal nontransformed tissues are not clear.

Researchers identified a Mtb effector protein, mammalian cell entry 3C (Mce3C), which promotes host cell necroptosis while inhibiting apoptosis. Mechanistically, Mtb Mce3C can bind host cathepsin ...

The experiment also revealed a rapid transition from apoptosis (natural programmed cell death) to late apoptosis/necrosis (cell death due to external toxins) between 3 and 24 h post-treatment. Indeed, ...

Two of the mechanisms that regulate the cell death process are apoptosis and necrosis. Apoptosis is a highly regulated process that involves the activation of cysteine-dependent aspartate-directed ...

Intracerebral hemorrhage (ICH) is a destructive form of stroke that often results in death or disability. However, the survivors usually experience sequelae of neurological impairments and psychiatric ...