Newly diagnosed PTCL; Two dose regimes of golidocitinib combined with CHOP have been explored for the treatment of newly ...

A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, ...

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity ...

The first-line standard of care for HR-positive/HER2-negative breast cancer is cyclin-dependent kinase (CDK)4/6 inhibitors ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...

Zanubrutinib combined with R-CHOP showed high efficacy in DLBCL patients with activated BCR signaling and specific genetic mutations, achieving a 91.4% ORR and 79.3% CR rate. The study's primary ...

When cells can’t destroy damaged proteins, a hidden backup system led by NRF1 steps in to prevent toxic buildup.

The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.

African Swine Fever Virus, ASFV, Viral Entry, Host Cell Invasion, CD163, Siglec-1, Macropinocytosis, Endosomal Escape, Immune Evasion, Signaling Pathways Share and Cite: Marcelino, K.B. and Fang, G.J.

By manipulating this pathway, scientists may be able to tweak the immune response to treat cancers, autoimmune disorders, and more.

Kazia Therapeutics Limited ("Kazia" or the "Company")  today announced new data from two presentations at the 2025 San Antonio Breast Cancer Symposium (SABCS) providing compelling mechanistic and ...