Vadimezan(DMXAA,AbMole,M1999)是一种多生物学活性的小分子化合物,其作用机理主要涉及三个方面:首先,Vadimezan(DMXAA)是一种STING激动剂,可通过激活STING信号通路诱导I型干扰素分泌促进免疫应答;其次,V ...
Onctura, a clinical-stage biopharmaceutical company combating neglected and hard-to-treat cancers, today announces it has dosed the first patient in its Phase I/II clinical trial evaluating ...
TARA-002 demonstrates 72% complete response rate at any time in BCG-Naïve patientsTARA-002 demonstrates a 69% complete response rate at the ...
A new nanoparticle vaccine successfully prevented several aggressive cancers in mice, including pancreatic and melanoma. The ...
Study targets patients with advanced disease who have progressed on prior immunotherapy CatalYmtoday announced that the first patient has been dosed in the randomized Phase 2b GDFATHER-NSCLC-02 ...
Vestibular Migraine (VM) is a common clinical neurological disorder characterized by recurrent episodes of dizziness and headaches. It has a significant genetic predisposition and a high morbidity and ...
Over the past two decades, thoracic oncology has undergone a profound transformation, moving from limited chemotherapy ...
Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic ...
This report provides useful evidence that EABR mRNA is at least as effective as standard S mRNA vaccines for the SARS-CoV-2 booster vaccine. Although the methodology and the experimental approaches ...
Blood Cancer United®—formerly The Leukemia & Lymphoma Society—will celebrate new data presented by Blood Cancer United funded ...
Spinal Cord Injury (SCI) is a devastating neurological disorder that often leads to permanent neural dysfunction. Current ...
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