Nature18d
Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling
Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...
EurekAlert!3d
Unraveling the role of the Wnt pathway in hepatocellular carcinoma: From molecular mechanisms to therapeutic implications
Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have ...
Medscape4d
Hepatic Fibrosis -- Role of Hepatic Stellate Cell Activation
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...
News Medical on MSN2d
Novel therapeutic approaches targeting the Wnt pathway in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates.
TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study
Morphogens are a class of secreted signaling factors that form concentration gradients between cells ... the TGF-β Dauer ...