Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Beta Bionics' listing consolidates views shared by investors that the healthcare fundraising landscape is recovering. Experts have forecast a rise in the volume and deals of IPOs this year as investor ...

Increased levels of glucose in the circulation lead to increased glucose uptake into pancreatic beta cells through GLUT2, a glucose transporter. Increased intracellular glucose then leads to ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

For example, beta cells secrete insulin in response to increased blood glucose levels, and this stimulates cells to take up glucose, an essential step in energy homeostasis. In contrast ...