provides a genome-wide query coverage metric (qcovGnm), which enables accurate interpretation of search results - particularly for circular queries (such as plasmid, virus, and mtDNA) against both ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

Abstract: Sequence-to-graph alignment is a critical component of pan-genome-based read alignment and represents the most computationally intensive step in this process. To address this challenge, we ...

Abstract: For decades, sequence-to-sequence alignment is a crucial tool in bioinformatics that identifies the similarity between a query and the reference genome sequence. Because one single reference ...

Callum Murray is a writer based in the North of England. His love of movies and television formed as a young child, and it continues to flourish. Dexter: Resurrection may revisit the original title ...

1 Image and Signal Processing Group, Institute for Computer Science, Leipzig University, Leipzig, Germany 2 Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig, ...

Parallel sequence alignment program that finds the optimal mutation in one sequence of the other. Parallelizes CPU and GPU using OpenMP and CUDA, and communicates with multiple computers using MPI.

ABSTRACT: While the mutational processes that subsume biological diversity can be revealed in great detail through phylogenetic inferencing using plastid markers, few studies document their use.