The centrosome is the major microtubule-organizing centre (MTOC) in eukaryotic cells, being comprised of two centrioles surrounded by an electron-dense matrix, the pericentriolar material (PCM). The ...

The primary function of the nucleolus is as the site of ribosome-subunit biogenesis in eukaryotic cells. The initial ribosomal RNA (rRNA) precursor is transcribed by RNA polymerase I and is ...

Recent advances in single cell RNA-seq (scRNA-seq) have enabled an unprecedented level of granularity in characterizing gene expression changes in disease models. Multiple single cell analysis ...