初始 T 细胞（Naive T cell，也叫做幼稚 T 细胞）是一类未接触过抗原的 T 细胞，处于静息（未活化）状态，它们尚未经历抗原特异性激活，但具有识别抗原的潜能，识别特异性抗原后，它们可分化为效应 T 细胞或记忆 T 细胞。

The 2025 Nobel Prize in Physiology or Medicine has been awarded to three scientists who discovered how our bodies keep this ...

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded the prize "for their discoveries concerning peripheral immune tolerance" ...

Scientists have found a way to transform hard-to-treat tumors into targets for the immune system. Using two protein stimulators, they activated strong T-cell and B-cell responses and built immune ...

Talha Burki speaks with Fred Ramsdell, Mary Brunkow, and Shimon Sakaguchi about their Nobel-winning discoveries in peripheral immune tolerance.

The indolent lymphoma market is witnessing steady growth driven by the increasing prevalence of slow-growing non-Hodgkin ...

Researchers at the University of Missouri School of Medicine have recently found that a certain protein may have a large ...

The impact of IL10 mutation in birds highlights the intrinsic compromise between effective elimination of a pathogen and damage to the host.

STAT Wunderkind Sydney Ramirez is revealing the immune system in our nasal passages and working toward better disease ...

美国学者 Mary E. Brunkow、Fred Ramsdell 和日本学者坂口志文（Shimon Sakaguchi），在外周免疫耐受领域的开创性发现成功鉴定出调节性 T 细胞，并揭示了免疫系统如何被调控以防止自我攻击，因此荣获 2025 ...