Cytochrome P450 enzymes (CYPs) are a large family of enzymes that play a crucial role in the metabolism of various substances, including drugs, toxins, and endogenous compounds. These enzymes are ...

In CB91, each atropisomer is metabolized at a similar rate. Figure 3: Human CYP enzymes’ metabolite formation activity against chiral PCB atropisomers Figure 4: Docking model of human CYP enzyme ...

Aim: The present study aimed to investigate the human genetic diversity of the CYP450 superfamily in order to identify functional interethnic differences and analyze the role of CYP450 enzymes in ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...