Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

UCSF scientists discover how cancer cells hijack the protein factory of the cell to churn out MYC protein, the driver of 70% ...

Hepatobiliary cancers, which include biliary tract cancer (BTC) and hepatocellular carcinoma (HCC), are among the most lethal ...

Feb. 10, 2025 — Influenza A virus particles strategically adapt their shape -- to become either spheres or larger filaments -- to favor their ability to infect cells depending on environmental ...

SCIENTISTS have discovered a “switch” that they say reverses cancer cells in a major development for finding a cure to the ...

Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

Kirsten rat sarcoma (KRAS) is a potent oncogenic driver that results in the downstream hyperactivation of MAPK signaling while simultaneously increasing replication stress (RS) and accumulation of DNA ...

“This is potentially a totally new biology that we were not looking at.” Further studies are needed to understand this phenomenon’s frequency and how much it benefits cancer cells, he add ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to ...

Except for a few cell types, such as blood or immune cells. But cancer cells also cross established boundaries, grow into the surrounding tissue and multiply. And they can detach from the cell ...

Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

They saw that extracellular matrix fibres at the outer edges of tumours pointed away from the malignancy, providing a “track” ...