在一项研究中，加州大学欧文分校（UC Irvine）生物化学系的研究人员在《Nature Communications》期刊上发表了一篇论文，揭示了白色念珠菌（Candida albicans）的Als蛋白如何通过劫持宿主细胞的死亡效应结构域（DEDs），促进炎性小体信号传导，从而引发强烈的免疫反应。这一发现不仅为理解真菌感染的分子机制提供了新的视角，还为开发针对念珠菌感染的新疗法提供了潜在的靶点 ...

Figure 1: Mitochondrial involvement in cell death. Mitochondria are organelles with two well-defined compartments: the matrix, surrounded by the inner membrane (IM), and the intermembrane space ...

Repeats Raise Risk. The more STR expansions a person carried, the higher their odds for AD (left). People with more repeat expansions tended to have worse tau pathology as per Braak stage (right).