Some caspases have long prodomains containing special motif such as DED (caspase-8 and -10), and caspase recruitment domains (CARD) (caspase-1, -2, -4, -5, -9, -11 and -12), which allow for ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

Cisplatin is widely used to treat various solid tumors. However, its toxicity to normal tissues limits its clinical application, particularly due to its ototoxic effects, which can result in hearing ...

You have full access to this article via your institution. Figure 2: Differential interaction of Apo2L trail versions with hepatocytes.

In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

Université de Bourgogne, U1231 INSERM, CTM, Equipe DesCarTes, UFR Sciences de Santé, 7 Bd Jeanne d’Arc, 21078 Dijon Cedex, France ...