Tissue expansion, originally developed for super-resolution imaging, has become a foundation for expansion omics (ExO), a ...

C2S-Scale converts a high-dimensional expression vector into text by rank-ordering genes and emitting the top-K symbols as a gene-name sequence. This representation aligns single-cell data with ...

Researchers at the University of Cambridge have developed a lab-grown embryo-like model called “hematoids”, which self-organises from stem cells to mimic very early human development. After about two ...

Scientists have grown a human embryo-like structure in a lab which replicates very early human development - including the production of blood stem cells. The lab-grown embryo model could help ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, and its ...

Abstract: Cell aspiration is a common micro-manipulation technique for cell transfer, particularly in in vitro fertilization (IVF) procedures. The minuscule volume of a cell (pL) and limited damping ...

Stem cell-based human embryo models (SCBEMs), generated in vitro from stem cells, currently exist outside the scope of regulatory frameworks that govern in vitro embryo research in most jurisdictions.

This fundamental work substantially advances our understanding of the molecular basis by which early symmetry breaking events connect to the following cell fate specifications in preimplantation ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...