Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment involves CD8⁺ T cells, also known as killer T cells, which play a crucial role ...
Clinical Trials Arena on MSN

Biosion doses first patient in phase Ia/Ib BSI-082 trial for solid tumours

The trial is conducted at the Mays Cancer Center, part of the University of Texas at San Antonio’s Health Science Center.
BMJ Case Reports

Use of intravenous immunoglobulin in combination with corticosteroids for immune checkpoint ...

Immune checkpoint inhibitor (ICI) pneumonitis is a potentially life-threatening immune-related adverse event associated with ICI therapy across various malignancies. ICIs enhance antitumour immunity ...
eLife

Mast cells promote pathology and susceptibility in tuberculosis

Conserved mast-cell activation, marked by elevated protease expression, aligns with progressive tuberculosis across human, macaque, and murine models.
Nanowerk

Magnetic nanoparticles reprogram T cells in vivo to eradicate solid tumors

Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...
allAfrica.com on MSN

TB Harnesses Part of Immune Defence System to Cause Infection

Scientists from the University of Cape Town's (UCT) Institute of Infectious Disease and Molecular Medicine (IDM) have contributed to an international study that shed new light on why humans and ...
AZoNano

Emerging Nanoplatforms in Biopharma: LNPs, Exosomes, Smart Nanocarriers

Learn which nanocarriers matter now (LNPs, exosomes, polymers) and the key hurdles in biodistribution, safety, CMC, and ...