The estrogen-induced gene modules in females were enriched for anatomical development functions and strongly correlated to the expression of several Z sex chromosome genes. We present a hypothesis ...

Summary: The authors perform a remarkably comprehensive, rigorous, and extensive investigation into the spatiotemporal dynamics between ribosomal accumulation, nucleoid segregation, and cell division.

The results showed that H3K4me3 accumulates abundantly on the cell membrane side of chromosomes. This accumulation was found to be specific to certain chromosomes such as the X chromosomes, and the ...

Flip open a high-school biology textbook, and the rule seems tidy: two X chromosomes mean girl, and an X paired with a Y means boy. That much smaller Y chromosome carries the SRY gene, which is the ...

X chromosome inactivation (XCI) is a mammalian dosage compensation mechanism that ensures balanced expression of X-linked genes between males and females. Research using rodent models has led to major ...

The retinoblastoma tumour suppressor pRB, the E2F transcription factor and related proteins are conserved in many species of plants and animals. Genetic and biochemical experiments now show that ...

Description Diagram of generic plant and animal cells, showing major organelles including nucleus, nucleolus, rough endoplasmic reticulum, smooth endoplasmic reticulum, cell membranes, golgi apparatus ...

Down syndrome is caused by an extra copy of chromosome 21, which leads to a range of developmental differences. Researchers have long sought strategies to correct this duplication, because current ...