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综述:COX-2的作用及其作为IBD和相关结直肠癌治疗靶点的研究
这篇综述系统阐述了环氧合酶-2(COX-2)在炎症性肠病(IBD)和结直肠癌(CRC)中的双重作用机制,揭示了其通过前列腺素(prostanoids)通路介导炎症反应、肿瘤微环境调控及血管生成的关键角色。文章重点探讨了COX-2基因多态性与疾病风险的关联性,并评述了 ...
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