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Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...
cell:解密dna的“朋友圈”!新型光交联技术精准捕获dna直接结合蛋白质. 来源:生物探索 2025-05-29 10:02. 研究不仅揭示了此前未知的dna互作蛋白质组的 ...
近日,德国慕尼黑工业大学等机构的研究人员开发出一种基于光交联的策略,可定量活细胞中与DNA直接接触的蛋白质。这项研究成果于5月22日发表在《Cell》杂志上。 与基因组相互作用的蛋白质决定着细胞的命运,也往往决定着 ...
Xing Kang et al, Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors, Cell (2025). DOI: 10.1016/j.cell.2025.04.012.
伯明翰大学的研究人员发现了答案,为解释两个长期存在疑问的特定DNA修复过程提供了细节。这两篇论文的发表表明,伯明翰大学的实验室在理解修复过程的正确安排方面取得了长足的进步。 伯明翰大学的研究人员发现了答案 ...
尿液游离 DNA(ucfDNA)是一种极具价值的真正无创液体活检资源。ucfDNA 包括两部分:经肾 ucfDNA(从血液流经肾小球滤过至尿液)和局部脱落的泌尿道 ...
Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed ...
The scientists analyzed the structure of the connector – the core of the phi29 DNA packaging motor – to a resolution of 3.2 angstroms, or 3.2 hundred-millionths of a centimeter. Their findings show ...
The solution structure of the human barrier-to-autointegration factor, BAF, a 21,000 Mr dimer, has been solved by NMR, including extensive use of dipolar couplings which provide a priori long ...
He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...
In addition to nuclear DNA, some DNA is present in energy-producing mitochondria, small organelles found free-floating in the cytoplasm, the area of the cell outside the nucleus. The three types of ...
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