CRISPR-based genome editing has considerable therapeutic potential in a wide range of diseases 1,2,3,4,5. A key challenge is achieving efficient, clinically suitable ...

Chemical insight into biological function is the holy grail of structural biology. Small molecules are central players as building blocks, effectors and probes of macromolecular structure and function ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect -- until now. Using what they describe as a 'chemical ...

In 1963, Popular Science reported on the Nobel Prize-winning discovery, and the woman who was left out of the accolades. By Bill Gourgey Published May 31, 2022 7:00 ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

SEATTLE — Jan. 5, 2012 — Researchers at Fred Hutchinson Cancer Research Center have solved the three-dimensional structure of a newly discovered type of gene-targeting protein that has shown to be ...

RNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the ...

DNA Full Form: The full name of DNA is Deoxyribonucleic Acid. This molecule holds the complete genetic code of living organisms. The name “Deoxyribonucleic Acid” reflects its part: “Deoxy” points to ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

When commissioned to design the facade and interior of the Institute of Molecular Genetics for the Czech Academy of Science, the Prague-based firm Studio P-H-A decided to add some bling to biomedicine ...